Significantly higher frequencies of presence of serum autoantibodies in Chinese patients with oral lichen planus

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Significantly higher frequencies of presence of serum autoantibodies in Chinese patients with oral lichen planus.

BACKGROUND Previous studies have shown the presence of serum anti-nuclear (ANA), anti-smooth muscle (SMA), anti-mitochondrial (AMA), anti-gastric parietal cell (GPCA), anti-thyroglobulin (TGA) and anti-thyroid microsomal autoantibodies (TMA) in small groups of patients with oral lichen planus (OLP). METHODS In this study, the serum levels of ANA, SMA, AMA, GPCA, TGA and TMA were measured in a...

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Comparison of Serum Autoantibodies to Desmogleins I, III in Patients with Oral Lichen Planus and Healthy Controls

Background & Objective: Lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. Desmogleins I and III are the main desmosomal transmembrane proteins. These proteins have been identified as the autoantigen of the autoimmune disease. The aim...

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Evaluation of serum Malondialdehyde level in patients with oral lichen planus

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress ...

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Serum autoantibodies to desmogleins 1 and 3 in patients with oral lichen planus.

AIM To determine the presence of circulating autoantibodies to desmoglein (Dsg) 1 and Dsg 3 in patients with oral lichen planus. METHODS Serum concentrations of circulating autoantibodies to Dsg 1 and Dsg 3 were determined by ELISA in 32 patients with erosive form and 25 patients with reticular form of oral lichen planus, 13 patients with acute recurrent aphthous ulcerations and 50 healthy co...

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Serum and salivary levels of vitamin D in oral lichen planus patients

Introduction: Vitamin D has anti-inflammatory and immunomodulatory function. The role of vitamin D deficiency has been established in the development of many types of cancers and autoimmune diseases. Oral lichen planus (OLP) is a common chronic autoimmune in oral cavity. This study aimed to evaluate the serum and salivary levels of total vitamin 25 (OH) D3 in patients with the OLP and to assess...

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ژورنال

عنوان ژورنال: Journal of Oral Pathology & Medicine

سال: 2008

ISSN: 0904-2512

DOI: 10.1111/j.1600-0714.2008.00686.x